The movie opens in 1969 at Skyview, a glamorous new high-rise restaurant where young couple Paul (Max Lloyd-Jones) and Iris (Brec Bassinger) are on a date. Iris, nervous about heights, is unsettled by a mischievous kid stealing a penny from a wishing fountain and stomping on the elevator’s glass floor. At the restaurant, a bartender’s mishap sends a wine bottle cap into a chandelier, cracking the reinforced glass floor. Iris, secretly pregnant and anxious about telling Paul, retreats to the bathroom, where she meets a singer who encourages her to embrace her happiness.
The night takes a romantic turn when Paul proposes to Iris on the observation deck, and her revelation about the pregnancy is met with joy. But the moment is shattered when the troublesome kid tosses pennies off the deck, one of which falls into the ventilation system, triggering a gas leak. As Paul and Iris dance on the glass floor, it shatters, plunging guests to their deaths, including Paul. A gas-fueled explosion engulfs the restaurant, and Iris barely survives a series of catastrophic events: a plummeting elevator, collapsing stairs, and a falling piano triggered by that fateful penny. In a desperate act, Iris saves the singer’s son, only to fall to her death, impaled by a glass shard.
But this is no ordinary tragedy—it’s a premonition. The scene cuts to the present day, where Stefani Reyes (Kaitlyn Santa Juana) wakes screaming from this nightmare, revealing Iris as her estranged grandmother.
Stefani, a college student plagued by the Skyview premonition, sees her grades slip and decides to return home for answers. Reuniting with her father, Marty (Tinpo Lee), and brother, Charlie (Teo Briones), she senses tension—Marty blames Iris for his wife Darlene’s (Rya Kihlstedt) abandonment, and Charlie resents Stefani’s absence since she left for college. Seeking clarity, Stefani visits her cousins—Julia (Anna Lore), Erik (Richard Harmon), and Bobby Campbell (Owen Patrick Joyner)—and their parents, Howard (Alex Zahara) and Brenda (April Telek).
Howard reveals Iris’s traumatic past, shaped by paranoia after surviving the Skyview disaster. Brenda secretly shares Iris’s letters warning of Death’s pursuit, leading Stefani to track down her grandmother (now played by Gabrielle Rose). Iris, dying of cancer and living in a fortified compound, shares a notebook detailing Death’s pattern, connecting Skyview to other disasters like the Route 23 pileup (Final Destination 2) and Flight 180 (Final Destination). Iris explains she saved everyone in her premonition, but Death is now targeting her bloodline, as they “were never supposed to exist.”
When Iris urges Stefani to stay in the compound, Stefani flees, only for Death to claim Iris with a gruesome weathervane accident. At Iris’s funeral, Stefani reconnects with her mother, Darlene, now a nomadic RV dweller. Tensions flare as Stefani and Charlie confront Darlene’s abandonment, mirroring Stefani’s own absence from Charlie’s life.
The Campbell family’s memorial barbecue turns deadly when a series of near-misses—a faulty gas tank, a misplaced rake, a shard of glass in a drink—foreshadow Death’s approach. Darlene averts one disaster, but a chain reaction involving a Hice Pale Ale bottle and a hose leads to Howard’s gruesome death by lawnmower. Stefani, armed with Iris’s notebook, warns the family that Death is targeting Iris’s relatives in order: Howard, Erik, Bobby, Julia, Darlene, Stefani, and Charlie.
Skepticism gives way to belief after Erik narrowly escapes a fiery accident at a tattoo parlor, and Julia meets a horrific end in a garbage compactor. The family seeks out William John Bludworth (Tony Todd), the singer’s son from Skyview, now a hospital worker and Iris’s confidant. Bludworth explains Death’s rules: to escape, one must either kill another to take their life (as in Final Destination 5) or die and be revived (as in Final Destination 2). With his own time running out, Bludworth bids them farewell.
In a desperate bid to cheat Death, Erik and Bobby attempt a risky plan in an MRI room, where a peanut butter cup triggers Bobby’s allergy. The plan backfires, and Erik is killed by the MRI’s magnet, while Bobby succumbs to a flying vending machine coil. Only Stefani, Charlie, and Darlene remain. Darlene sacrifices herself to secure Iris’s compound, but an explosion claims her life. Charlie revives Stefani from drowning, and they believe they’ve outsmarted Death.
As Stefani prepares to return to college, she sends Charlie to his prom. An old lady drops a penny—eerily similar to the Skyview coin—onto train tracks, triggering a derailment. Stefani realizes her revival didn’t break Death’s cycle, as her heart never stopped. As the siblings flee, logs from the train crush them both. The credits roll with newspaper clippings of Skyview survivors’ deaths, ending with Stefani and Charlie’s obituary and a poignant in memoriam for Tony Todd[wide].
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